Diabetic neuropathies (DNs) or polyneuropathies are the most common complications of diabetes mellitus (DM) and encompass a group of nerve disorders. DNs affect about 60-70% of overall population with diabetes and up to 50% among older adults with Type 2 DM. The occurrence of neuropathies usually represents the late and chronic complications of long standing diabetes mellitus and involves nerve tissue damage or abnormal changes in both the cranial and peripheral nerves.